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New blood test identifies TB infections within hours

28 Mar 2017 | 10:35 AM

WASHINGTON:US researchers said they have successfully developed a blood test that can rapidly diagnose and quantitate the severity of active tuberculosis (TB) cases, an important advance against the major global health threat, a media report said.

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Washington

US researchers said they have successfully developed a blood test that can rapidly diagnose and quantitate the severity of active tuberculosis (TB) cases, an important advance against the major global health threat, a media report said.

"In the current frontlines of TB testing, coughed-up sputum, blood culture tests, invasive lung and lymph biopsies, or spinal taps are the only way to diagnose TB," said Tony Hu of the Arizona State University on Monday.

"The results can give false negatives, and these tests are further constrained because they must take days to weeks to get the results," Xinhua news agency quoted Hu as saying.

The new method combines antibody-labelled nanoparticles with high-throughput mass spectrometry to measure small molecules known as peptides from Mycobacterium tuberculosis in the detection of active TB infections, reported in the US journal Proceedings of the National Academy of Sciences.

The team said their newly developed NanoDisk-MS assay not only outperforms all others currently on the market but also takes just hours to complete.

This is a very important advance because effective TB control requires that patients should be treated as soon as possible to reduce the risk of spreading the disease, the researchers said.

This assay could also significantly improve TB diagnosis and management because it is the first test that can measure the severity of active TB infections.

It does so by accurately detecting minute blood levels of two proteins, known as CFP-10 and ESAT-6, which TB bacteria release only during active infections.

"We are particularly excited about the ability of our high-throughput assay to provide rapid quantitative results that can be used to monitor treatment effects, which will give physicians the ability to better treat worldwide TB infections," Hu added.

According to the World Health Organisation (WHO), TB remains a major global health problem, with 10 million cases and 2 million deaths per year.

Making matters worse, TB bacteria can lurk in a person's lung tissue for decades, before spontaneously producing full blown TB disease that can then spread to others. Currently, the WHO estimates that up to one-third of the world's population may have such dormant TB infections.

—IANS

New blood test identifies TB infections within hoursTB remains a major global health problem, with 10 million cases and 2 million deaths per year.
Nut allergy tests may be inaccurate

Nut allergy tests may be inaccurate

28 Mar 2017 | 10:34 AM

WASHINGTON: Being allergic to one type of nut may not mean that you need to stop eating all other nuts, according to scientists who claim that certain diagnostic tests may be unreliable.

Choose sunscreen according to your skin tone

Choose sunscreen according to your skin tone

27 Mar 2017 | 2:02 PM

NEW DELHI: Sun protection is essential throughout the year, but it gets yet more important during the summers. Protecting the skin from excessive exposure is the only way to prevent it from aging, sun burns, and skin discoloration.

Cutting salt intake may lower night-time toilet trips

Cutting salt intake may lower night-time toilet trips

26 Mar 2017 | 8:13 PM

TOKYO: Lowering salt intake can significantly reduce excessive night time toilet trips, a condition which is also known as nocturia, a new study has found.

Sleepless night may impair ability to recognise expressions

Sleepless night may impair ability to recognise expressions

26 Mar 2017 | 5:37 PM

LOS ANGELES: Didn’t sleep well last night? You may have a hard time identifying whether people around you are happy or sad, scientists say.

Children with autism may benefit from faecal transplant

Children with autism may benefit from faecal transplant

26 Mar 2017 | 1:11 PM

Faecal transplants – a method of introducing donated healthy microbes into people with gastrointestinal disease to rebalance the gut — may benefit children suffering from autism, a new study has suggested.

Childhood brain cancer survivors at higher heart disease risk

Childhood brain cancer survivors at higher heart disease risk

25 Mar 2017 | 8:51 PM

TORONTO: Survivors of childhood brain tumours are at an increased risk of heart disease, Type 2 diabetes and early death because of higher overall fat tissue, a new study has warned.

10 mins of vigorous exercise may cut diabetes risk in kids

10 mins of vigorous exercise may cut diabetes risk in kids

25 Mar 2017 | 9:02 PM

WASHINGTON: Ten minutes of high-intensity physical activity every day may help some children reduce their risk of developing heart problems and metabolic diseases such as diabetes, a new study claims.

Mother's hug may boost immunity, health of baby

Mother's hug may boost immunity, health of baby

24 Mar 2017 | 4:11 PM

NEW DELHI:A mother's hug can boost immunity, stabilise heart rate and maintain body temperature of the baby, say doctors in a survey which shows that an embrace does more than simply putting a smile on your little one's face.

Weight-bearing exercises may boost bone health in men

Weight-bearing exercises may boost bone health in men

23 Mar 2017 | 9:38 PM

LOS ANGELES: Practicing weight-bearing exercises such as resistance training and various types of jumps may increase bone density in men, a new study has found.

India urged to intensify research for multi-drug resistant TB

India urged to intensify research for multi-drug resistant TB

23 Mar 2017 | 9:31 PM

NEW DELHI: As India continues to account for 24 per cent of the world's total Tuberculosis (TB) burden, the Indian Society for Clinical Research (ISCR) on Thursday called for a comprehensive research in multi-drug resistant Tuberculosis, citing that resistance to antimicrobials is growing at a faster rate than discovery of newer and more potent drugs.

New test may predict onset of Alzheimer's

New test may predict onset of Alzheimer's

22 Mar 2017 | 10:59 PM

LOS ANGELES:A new test that allows individuals to calculate their age-specific risk of Alzheimer's disease based on their genetic information has been developed by researchers including one of Indian origin.

Simple blood test may help detect cancer early

Simple blood test may help detect cancer early

21 Mar 2017 | 1:55 PM

NEW YORK: Now doctors may soon be able to detect and monitor a patient's cancer with a simple blood test, reducing or eliminating the need for more invasive procedures, according to a new research.

Functional 'beating' human heart muscle created

Functional 'beating' human heart muscle created

20 Mar 2017 | 9:44 PM

MELBOURNE: Scientists have created a functional 'beating' human heart muscle from stem cells, a significant step forward in cardiac disease research.

Your high BP might just be a case of misdiagnosis

Your high BP might just be a case of misdiagnosis

20 Mar 2017 | 12:59 PM

TORONTO: Nearly 20 per cent of people receiving treatment for hypertension do not actually have a problem, but they are often misdiagnosed as a result of doctors using manual devices to measure blood pressure, a study has showed.

Scientific breakthrough to aid malaria vacccine research

Scientific breakthrough to aid malaria vacccine research

20 Mar 2017 | 12:51 PM

CANBERRA: Australian scientists have discovered a "key molecule", which can kill microbes that infect the human liver, a breakthrough experts believe could bring a malaria vaccine one step closer.

Skinny jeans, high heels may impact women’s health

Skinny jeans, high heels may impact women’s health

19 Mar 2017 | 10:14 PM

LONDON: Love skinny jeans, oversized bags and high heels? These fashion choices may be damaging your body, scientists have warned.

New lip-reading AI system may help people with hearing loss

New lip-reading AI system may help people with hearing loss

19 Mar 2017 | 9:56 PM

LONDON: Oxford scientists have developed a new artificial intelligence programme that can lip-read more accurately than people, an advance that will help those who suffer from hearing loss.

Sleep apnea in children may impact brain development

Sleep apnea in children may impact brain development

18 Mar 2017 | 10:46 PM

WASHINGTON:Untreated sleep apnea in children causes loss of grey matter - brain cells involved in movement, memory, emotions, speech, perception, decision making and self-control, researchers including one of Indian origin have found.

First blood test for autism developed

First blood test for autism developed

17 Mar 2017 | 12:53 PM

WASHINGTON: In a first, scientists have discovered a way to accurately predict whether a child has autism spectrum disorder by analysing a blood sample, an advance that opens the door to earlier diagnosis and potential future development of therapeutics.

A cup of tea daily may lower risk of dementia

A cup of tea daily may lower risk of dementia

17 Mar 2017 | 10:37 AM

WASHINGTON DC: Good news for tea lovers, as a study finds drinking just one cup of tea daily may significantly lower the risk of dementia by 50 per cent.

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